TENOLAM E Tablet is an antiretroviral medication used to treat HIV-1 infection and manage chronic hepatitis B virus (HBV) infection. It contains a combination of two active ingredients, Tenofovir disoproxil fumarate (TDF) and Lamivudine (3TC), which are nucleoside reverse transcriptase inhibitors (NRTIs). These medications work by inhibiting the replication of the viruses, reducing viral load, and preventing damage to the immune system or liver.

Key Features:

• Active Ingredients:
• Tenofovir disoproxil fumarate (TDF) – 300 mg
• Lamivudine (3TC) – 300 mg
• Formulation: Oral tablet
• Indications:
• Treatment of HIV-1 disease as a feature of mix antiretroviral treatment.
• Management of chronic hepatitis B (HBV) in appropriate cases.

How TENOLAM E Tablet Works:

TENOLAM E inhibits the activity of reverse transcriptase, an enzyme required for the replication of HIV and HBV. By blocking this enzyme, the medication helps control the progression of these infections, protecting the immune system and preventing further complications.

Dosage and Administration:

• HIV Treatment: Take 1 tablet daily in combination with other antiretroviral medications as prescribed.
• Hepatitis B Treatment: The dosage and duration will be determined by the doctor based on the patient's condition.

The tablet can be taken with or without food, ideally at the same time each day.

Benefits of TENOLAM E Tablet:

1. Reduces viral load in the body.
2. Helps restore and protect the immune system in HIV patients.
3. Slows the progression of liver damage in chronic hepatitis B infection.
4. Convenient once-daily dosing for ease of adherence.

Common Side Effects:

• Nausea
• Diarrhea
• Fatigue
• Headache
• Dizziness

Rare but serious side effects may include:

• Kidney problems (e.g., renal dysfunction)
• Bone mineral density loss
• Lactic acidosis (rare but potentially life-threatening)

Precautions:

1. Kidney Function: Regular monitoring is necessary as Tenofovir may affect kidney health.
2. Bone Health: Patients with a history of osteoporosis or fractures should be closely monitored.
3. Hepatitis B: Stopping the medication abruptly can lead to severe HBV flares.
4. HIV Status: For HIV treatment, ensure adherence to avoid resistance development.

Storage Instructions:

• Store at room temperature (20-25°C) in a cool, dry spot.
• Keep away from moisture, heat, and direct sunlight.
• Keep out of the reach of children.

FAQs:

1. What is TENOLAM E Tablet used for?

TENOLAM E Tablet is used for:

• The treatment of HIV-1 infection as part of combination antiretroviral therapy.
• The management of chronic hepatitis B virus (HBV) infection in certain cases.

2. What are the active ingredients in TENOLAM E Tablet?

TENOLAM E contains:

• Tenofovir disoproxil fumarate (TDF) – 300 mg
• Lamivudine (3TC) – 300 mg
• Both are nucleoside reverse transcriptase inhibitors (NRTIs) that work to suppress the replication of HIV and HBV.

3. How does TENOLAM E Tablet work?

TENOLAM E blocks the activity of reverse transcriptase, an enzyme necessary for the replication of HIV and HBV. This helps reduce the viral load in the body, protects the immune system, and prevents further damage to the liver.

4. How should I take TENOLAM E Tablet?

• Take 1 tablet daily at the same time every day.
• It can be taken with or without food.
• Follow your healthcare provider’s instructions carefully.

5. Can TENOLAM E cure HIV or hepatitis B?

No, TENOLAM E does not cure HIV or hepatitis B. It helps to manage these infections by suppressing viral replication and reducing the risk of complications.

6. Can I stop taking TENOLAM E if I feel better?

No, don't quit taking TENOLAM E without talking with your PCP. Abruptly stopping the medication can lead to:

• A resurgence of HIV or HBV.
• Potential resistance to the medication in the case of HIV.
• Severe flares of hepatitis B if treating HBV.