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Hervycta Plus 440mg Injection is a combination targeted therapy used in the treatment of HER2-positive breast cancer. It contains two active ingredients, Trastuzumab and Pertuzumab, both monoclonal antibodies designed to specifically target the HER2 (human epidermal growth factor receptor 2) protein, which is overexpressed in certain cancer cells and contributes to tumor growth and survival.
Trastuzumab works by restricting to the HER2 receptor on disease cells, hindering the signs that advance cancer development. Pertuzumab further enhances the therapeutic effect by preventing HER2 from dimerizing with other receptors, which is essential for the activation of tumor-promoting signals. Together, these two antibodies work synergistically to inhibit cancer cell proliferation, effectively slowing or halting the growth of the tumor.
Key Features:
Precautions:
Common Side Effects: Fever, chills, nausea, fatigue, pain or swelling at the infusion site. Serious side effects may include heart problems, severe allergic reactions, and lung issues.
FAQs:
1.What is Hervycta Plus 440mg Injection used for?
Hervycta Plus 440mg Injection is used for the treatment of HER2-positive breast cancer. It contains two monoclonal antibodies, Trastuzumab and Pertuzumab, which work together to target and block the HER2 receptor, inhibiting tumor growth and spread.
2.How does Hervycta Plus work?
Trastuzumab binds to the HER2 receptor on cancer cells, blocking the signals that promote tumor growth. Pertuzumab prevents HER2 from pairing with other receptors, further disrupting cancer cell growth. This dual inhibition of the HER2 receptor is more effective in stopping cancer cell proliferation.
3.What is the typical dosage of Hervycta Plus 440mg?
The dosage of Hervycta Plus is based on the patient’s weight, overall health, and the specifics of their cancer condition. It is typically administered every 3 weeks, often in combination with chemotherapy or other cancer treatments, as prescribed by a healthcare provider.
4.What are the common side effects of Hervycta Plus 440mg Injection?
Common side effects include fever, chills, nausea, fatigue, and pain or swelling at the infusion site. Some patients may also experience flu-like symptoms such as headache, muscle aches, or joint pain.
5.Can Hervycta Plus be used with other cancer treatments?
Yes, Hervycta Plus is often used in combination with chemotherapy or other cancer therapies to increase its effectiveness in treating HER2-positive breast cancer. Your healthcare provider will decide the best treatment regimen for your specific condition.
6.How should Hervycta Plus be stored?
Hervycta Plus should be stored in the refrigerator (between 2°C and 8°C) and should be protected from light. It should not be frozen. Follow your healthcare provider’s instructions for proper disposal of unused vials.
7.Can I continue with my normal activities during treatment with Hervycta Plus?
Many patients can continue their regular activities during treatment with Hervycta Plus, but it is important to follow your healthcare provider’s advice regarding rest, diet, and any necessary lifestyle changes to manage side effects during treatment.